Care Evolution

Summary

Over-the-counter rapid antigen tests and innovations in mobile technology that rely on at-home self-administration and digital reporting offer an opportunity for a test-to-stay program for K-12 students that is safe and rigorous, yet scalable. Livingston County Health Department (LCHD) in Michigan—with support of the National Institute of Health’s (NIH’s) Rapid Acceleration of Diagnostics (RADx^®) Tech program’s Clinical Studies Core at UMass Chan Medical School and CareEvolution’s mobile health platform, MyDataHelps—developed a digitally enabled test-to-stay program relying on student (or guardian) self-administration and interpretation of at-home rapid antigen COVID-19 tests. A simple web application delivers an interconnected system allowing for real-time testing and results reporting for students exposed to a COVID-19 case in a school setting, reducing school and health department staff burden. This test-to-stay program also increases accessibility by employing a digital health platform, thus addressing some of inequity in participation seen with traditional programs. Initial concerns around technology adoption, test administration, and inaccurate test results were not observed. The program resulted in 3,653 student school days saved in the fall of 2021 (defined as any weekday where there was a negative test on the prior day or morning of an asymptomatic student presenting to school).

This project has been funded by the NIH RADx-Tech program in whole or in part with federal funds from the National Institute of Biomedical Imaging and Bioengineering (under Contract No. 75N92020P00146), and the National Heart, Lung, and Blood Institute (under 3U54HL143541-02S2), National Institutes of Health, Department of Health and Human Services.

Introduction

The aim of this pilot is to determine whether at-home rapid antigen testing along with the use of mobile technology can reduce the burden of a test-to-stay program for school administrators during the COVID-19 global pandemic. COVID-19 test-to-stay programs allow for asymptomatic students who are exposed to COVID-19 in the school environment to continue to attend in-person school for the duration of the student’s exclusion period by complying with testing and symptom screening. Without a school test-to-stay program, per evolving Centers for Disease Control and Prevention (CDC) and state health department guidelines, Livingston County (MI) students were excluded from in-person school for 7-10 days after a COVID-19 exposure. A traditional test-to-stay program requires significant coordination between schools, public health, and guardians to ensure testing consent is obtained from guardians and testing resources are made available to schools. Implementation often necessitates pooled testing, which is less actionable than individual testing. With support from NIH, The aim of this pilot is to determine whether at-home rapid antigen testing along with the use of mobile technology can reduce the burden of a test-to-stay program for school administrators during the COVID-19 global pandemic. COVID-19 test-to-stay programs allow for asymptomatic students who are exposed to COVID-19 in the school environment to continue to attend in-person school for the duration of the student’s exclusion period by complying with testing and symptom screening. Without a school test-to-stay program, per evolving Centers for Disease Control and Prevention (CDC) and state health department guidelines, Livingston County (MI) students were excluded from in-person school for 7-10 days after a COVID-19 exposure. A traditional test-to-stay program requires significant coordination between schools, public health, and guardians to ensure testing consent is obtained from guardians and testing resources are made available to schools. Implementation often necessitates pooled testing, which is less actionable than individual testing. With support from NIH, CareEvolution leveraged their digital health technology platform, MyDataHelps, to facilitate Livingston County Health Department’s (LCHD’s) implementation of a test-to-stay program to increase in-person school opportunities for students while also minimizing the burden for school staff. MyDataHelps provides a method for obtaining consent from guardians, distributing test kits to students’ homes, providing instructions to assist with at-home testing, and reporting individual antigen test results via summary dashboards. During the fall of 2021, 4,904 Livingston County students exposed to COVID-19 in the classroom were offered a test-to-stay option in which they could continue attending in-person school if they remained asymptomatic and tested negative on at-home antigen tests.

Guardian Enrollment

Test Administration Instructions

Actionable Results

Key distinctions between traditional test-to-stay programs and digitally-enabled test-to-stay programs

Time To Test Prompt

How the digitally-enabled program works

In lieu of in-person school exclusions for exposed, unvaccinated students who are close contacts of positive cases, the program offers an alternate strategy to maintain safe in-person education: daily at-home COVID-19 antigen testing and symptom screening during the student’s alternate attendance period. If the student remains asymptomatic and tests negative, the student can attend in-person school while masked. This program is voluntary; guardians can elect for their students to be excluded from in-person education after close contact with a positive case. Upon COVID-19 exposure and opt-in to the digitally-enabled test-to-stay program, a QuickVue At-Home OTC COVID-19 test kit is provided to guardians at the student’s school. The remaining test kits are shipped directly to the student’s home through an automated process powered by CareEvolution’s MyDataHelps platform. This alleviates the burden of storing and distributing test kits across the participating school districts, significantly reducing health department staff requirements for the program’s execution. This digital pilot test-to-stay program provides the opportunity for students to attend in-person school while limiting the burden on school staff.

Digitally-enabled test-to-stay workflow

1. Student is identified by school or local public health department as a close contact.
2. Upload a list of all close contacts to the MyDataHelps platform. Low risk students (e.g. vaccinated or recently infected) are excused and may continue attending in-person school.
   
3. For digitally-enabled test-to-stay ineligible students, close contacts are excluded from in-person school for the exclusion period (in the case of an outbreak, school is not participating, etc.).
   

   For digitally-enabled test-to-stay eligible students:

4. Guardians receive email and SMS to select how they would like to proceed:
   

   a. Digitally-enabled test-to-stay program

   b. In-person school exclusion

5. Students enrolled in test-to-stay are required to do daily testing and symptom checks through the web application. Based on test and symptom results, the app informs if the student (conditionally) can or cannot attend school that day.
6. If they neglect to test, report symptoms, or test positive, the student is automatically excluded from in-person school and the test-to-stay option ends for this student. The school is automatically notified through an online dashboard. If symptoms are present or the test results are positive, the student is automatically moved to in-person school exclusion for 10 days, without the option to test out on Day 6/7.
7. Students who are not enrolled in the digitally-enabled test-to-stay program do not attend school for the duration of the exclusion period.
8. Students can optionally test during the exclusion period. If their results are negative, they can return to in-person school on Day 8.

Actionable Results

School and Health Department staff involvement

Rather than relying on health department staff to obtain test and symptom data, manage shipment logistics for test kits, and inform school administrators regarding in-person school attendance, CareEvolution’s technology connects households, schools, and health departments to greatly reduce staff burden. The digitally-enabled test-to-stay program still relies on engagement and support from school and health department staff. School staff must access a population-specific attendance dashboard, understand its use and purpose, and ensure only the students who are following the proper protocols are in attendance. For health department staff, accurate and timely reporting of close contacts is necessary for the success of any test-to-stay program. In order to facilitate timely reporting of close contacts, a process must be established between the school and the health department. In addition to creating a communication link between the schools and the health department, CareEvolution’s technology also allows for efficient case investigation and follow-up of students who test positive for COVID-19, which is essential for controlling the spread of COVID-19 within a population. Without such technology, the process for individual case investigation would overburden health department staff and delay reporting which could lead to increased cases.

* LCHD Digitally-Enabled Test-to-Stay Pilot, Fall 2021

Future of test-to-stay

According to Pew Research, over 85% of Americans own a smartphone, including 80% of the rural population (Pew Research Center 2021b, Pew Research Center 2021a). Ninety percent (90%) of the US population regularly uses the internet. By leveraging accessible technology like MyDataHelps and expanding its reach, we can streamline test-to-stay programs by making them digitally-enabled. MyDataHelps provides a test-to-stay platform that obtains consent, ships test kits, facilitates test administration, collects results and symptoms, reports results, and sends notifications regarding school attendance status. MyDataHelps also provides a simple method for communicating changes in COVID-19 masking, testing, and vaccination guidance. By automating a test-to-stay program, school administrators and health department staff can deploy a test-to-stay program at scale, without significant burden.

The autonomous, private, and convenient nature of self-administered testing may increase uptake of testing in populations that may otherwise not test. This could be an indicator that the process of self-testing and logging results through the MyDataHelps web application offers a promising modality for supporting efforts to mitigate the spread of COVID-19 in communities.

As COVID-19 variants of concern continue to emerge, it is important to maintain a layered approach to mitigating disease transmission. In addition to masking and vaccination, testing is critical to further reduce the spread of COVID-19, especially in school communities. Implementation of a school testing protocol ensures that students can continue in-person education while minimizing risk to others. Test-to-stay programs offer a feasible option to implement a school testing protocol and safely allow students to continue in-person school. The CDC has since published guidance supporting test-to-stay programs, suggesting the need for effective test-to-stay programs and further supporting the adoption of test-to-stay programs in K-12 education (CDC, 2022b). Effective test-to-stay programs improve student developmental and educational outcomes, and households and communities additionally benefit by reducing the need for student home care (CDC, 2022a). As the United States pilots other initiatives to distribute rapid antigen at-home test kits, such as Say Yes! COVID Test (also powered by MyDataHelps), school districts and health departments should likewise consider scalable digital solutions to promote public health in school communities by leveraging the near real-time results of at-home tests. Through digitally enabled test-to-stay programs powered by technology like MyDataHelps, students, teachers, and communities across the world can have better access to health—not only during the COVID-19 pandemic, but in years to come.